Chunxiao Zhou Selected Research

ONC206

1/2022	ONC206 has anti-tumorigenic effects in human ovarian cancer cells and in a transgenic mouse model of high-grade serous ovarian cancer.
1/2021	Highly potent dopamine receptor D2 antagonist ONC206 demonstrates anti-tumorigenic activity in endometrial cancer.
1/2020	ONC206, an Imipridone Derivative, Induces Cell Death Through Activation of the Integrated Stress Response in Serous Endometrial Cancer In Vitro.

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Chunxiao Zhou Research Topics

Disease

40	Neoplasms (Cancer) 01/2022 - 01/2002
27	Endometrial Neoplasms (Endometrial Cancer) 01/2022 - 01/2002
20	Ovarian Neoplasms (Ovarian Cancer) 01/2022 - 03/2006
9	Obesity 11/2021 - 04/2014
3	Carcinogenesis 01/2013 - 11/2006
2	Hematologic Neoplasms (Hematological Malignancy) 02/2021 - 01/2021
2	Carcinoma (Carcinomatosis) 01/2018 - 08/2014
2	Neoplasm Metastasis (Metastasis) 01/2018 - 01/2015
2	Uterine Cervical Neoplasms (Cancer of the Cervix) 04/2017 - 03/2006
2	Hepatocellular Carcinoma (Hepatoma) 01/2013 - 10/2012
1	Hypersensitivity (Allergy) 01/2020
1	Immediate Hypersensitivity 01/2020
1	Pre-Eclampsia (Preeclampsia) 11/2019
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2019
1	Glioma (Gliomas) 01/2018
1	Lactic Acidosis 11/2017
1	Type 2 Diabetes Mellitus (MODY) 11/2017
1	Papillomavirus Infections 04/2017
1	Chromosomal Instability (Chromosome Stability) 01/2017
1	Weight Loss (Weight Reduction) 12/2016
1	Leiomyoma (Uterine Fibroids) 01/2016

Drug/Important Bio-Agent (IBA)

10	Messenger RNA (mRNA)IBA 02/2021 - 08/2003
9	Metformin (Glucophage)FDA LinkGeneric 11/2021 - 01/2010
8	Telomerase (Telomerase Reverse Transcriptase)IBA 01/2015 - 08/2003
7	Proteins (Proteins, Gene)FDA Link 01/2017 - 12/2008
6	TIC10 compoundIBA 01/2022 - 01/2018
5	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2022 - 06/2016
5	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 01/2015
5	MTOR InhibitorsIBA 04/2016 - 08/2003
5	Sirolimus (Rapamycin)FDA Link 12/2010 - 08/2003
4	Paclitaxel (Taxol)FDA LinkGeneric 01/2020 - 03/2010
4	Estrogens (Estrogen)FDA Link 01/2018 - 11/2006
3	ONC206IBA 01/2022 - 01/2020
3	LipidsIBA 02/2021 - 05/2006
3	Dopamine Receptors (Dopamine Receptor)IBA 02/2021 - 01/2020
3	BiguanidesIBA 01/2021 - 09/2016
3	Biological ProductsIBA 01/2021 - 01/2002
3	Transcription Factors (Transcription Factor)IBA 11/2019 - 04/2014
3	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2017 - 08/2014
2	Peptide Hydrolases (Proteases)FDA Link 01/2022 - 01/2022
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2022 - 01/2021
2	LigandsIBA 01/2022 - 01/2021
2	Pharmaceutical PreparationsIBA 01/2020 - 01/2013
2	Atorvastatin (Lipitor)FDA Link 01/2018 - 01/2017
2	Estrogen Receptor alphaIBA 01/2018 - 12/2008
2	Fatty Acids (Saturated Fatty Acids)IBA 12/2017 - 12/2016
2	Caspase 3 (Caspase-3)IBA 11/2017 - 08/2014
2	Glutamine (L-Glutamine)FDA Link 09/2017 - 08/2015
2	EnzymesIBA 12/2016 - 11/2006
2	Simvastatin (Zocor)FDA LinkGeneric 01/2016 - 08/2014
2	3' Untranslated Regions (3' UTR)IBA 01/2016 - 10/2012
2	Estrogen ReceptorsIBA 01/2013 - 11/2006
2	Mitogen-Activated Protein KinasesIBA 01/2013 - 12/2008
2	Biomarkers (Surrogate Marker)IBA 12/2010 - 08/2003
2	TOR Serine-Threonine KinasesIBA 03/2010 - 09/2009
2	Arsenic Trioxide (Trisenox)FDA Link 12/2008 - 04/2007
1	ipatasertibIBA 01/2022
1	Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA 01/2022
1	RNA (Ribonucleic Acid)IBA 11/2021
1	cremophor ELIBA 01/2020
1	Docosahexaenoic AcidsIBA 01/2020
1	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 01/2020
1	Fish OilsIBA 01/2020
1	ProdrugsIBA 01/2020
1	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 01/2020
1	Generic DrugsIBA 01/2019
1	GenisteinIBA 01/2018
1	IsoenzymesIBA 01/2018
1	Carbonic Anhydrases (Carbonic Anhydrase)IBA 01/2018
1	Progesterone Receptors (Progesterone Receptor)IBA 01/2018
1	Topiramate (Topamax)FDA LinkGeneric 01/2018
1	IsoflavonesIBA 01/2018
1	Carbonic Anhydrase IXIBA 01/2018
1	K-18 conjugate (K18)IBA 12/2017
1	Phenformin (Fenformin)IBA 11/2017
1	Aminooxyacetic AcidIBA 09/2017
1	Pyruvic Acid (Pyruvate)IBA 09/2017
1	Adenosine Triphosphate (ATP)IBA 09/2017
1	MicroRNAs (MicroRNA)IBA 04/2017
1	Orlistat (Xenical)FDA Link 12/2016
1	Fatty Acid Synthases (Fatty Acid Synthase)IBA 12/2016
1	Cyclin-Dependent Kinase 4IBA 10/2016
1	Cyclin D1IBA 10/2016
1	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 06/2016
1	Celecoxib (Celebrex)FDA Link 06/2016
1	Mechanistic Target of Rapamycin Complex 1IBA 04/2016
1	Everolimus FDA Link 04/2016
1	Phosphotransferases (Kinase)IBA 04/2016
1	VimentinIBA 01/2016
1	Mevalonic Acid (Mevalonate)IBA 01/2016
1	compound 968IBA 01/2016
1	GlutaminaseIBA 01/2016
1	BuforminIBA 01/2016

Therapy/Procedure

11	Therapeutics 01/2022 - 08/2003
6	Fat-Restricted Diet (Diet, Fat Restricted) 01/2022 - 04/2014
1	Curettage 01/2017
1	Aftercare (After-Treatment) 06/2016
1	Radiotherapy 01/2016
1	Cystectomy 01/2016
1	Hysterectomy 01/2016